Optimization of Carbon Paste Electrode Modified with Carbon Nanotube and Molecularly Imprinted Poly (3-aminophenol) for Voltammetric Determination of Paracetamol Abraham Mora (a), Indra Noviandri (b*)
a) Department of Chemistry Education, Universitas Pendidikan Indonesia
Jl. Dr. Setiabudi No.229, Isola, Bandung
b) Chemistry Department, Institut Teknologi Bandung
Jl. Ganesa No.10, Bandung
*innov[at]itb.ac.id
Abstract
Various methods had been developed for the analysis of paracetamol, including voltammetry techniques using carbon paste electrodes (CPE) as working electrodes. CPE has great electrical conductivity, easy-made, as well as economical price. However, CPE has drawbacks in terms of selectivity as many electroactive analytes could undergo redox reaction on the surface of CPE. Moreover, CPE needs to be modified with molecularly imprinted polymer (MIP) to improve selectivity.
In this research, we did a study to know the optimum condition in the fabrication of the modified working electrodes. We optimized the number of electropolymerization cycles, type of supporting electrolytes, and the concentration of dispersed CNT. As the result, carbon paste electrode modified by carbon nanotube and molecularly imprinted poly(3-aminophenol)-(CPE-CNT-MIP) as a working electrode had been successfully optimized. A 2 mg/ml carbon nanotube dispersant in DMF was dispersed over the CPE. Electropolymerization and removal process is conducted by cyclic voltammetry (CV) by 15 and 10 cycles respectively in the potential range of -0,2V-1,2V, with the scanning rate of 100 mV/s. HClO4 was used as a supporting electrolyte. These variables showed the best performance to analyze paracetamol samples using voltammetry.
