Flavonoid Content and Total Antioxidant Capacity of Coriander (Coriandrum sativum L.) Seed Extract in Different Level Polarity of Solvent Novi Silvia Hardiany1*, Fadilah2, Filda Vionita Irene de Lima3, Syarifah Dewi1, Irah Namirah4
1Department of Biochemistry & Molecular Biology, Faculty of Medicine Universitas Indonesia
2Department of Medical Chemistry, Faculty of Medicine Universitas Indonesia
3Magister Program of Biomedical Science, Faculty of Medicine Universitas Indonesia
4Doctoral Program of Biomedical Science, Faculty of Medicine Universitas Indonesia
Abstract
Coriander seeds are widely used as anti-pain, anti-inflammatory, anti-hyperglycemia and anti-hyperlipidemia in the traditional medical field. As an antioxidant, coriander seeds are also able to reduce the formation of free radicals due to the presence of polyphenolic compounds. In several studies it is known that coriander is capable of being a good radical scavenger in extracts in various solvents, however different solvents probably produce different phytochemical component. This study aimed to analyze the phytochemical components and total antioxidant activity of coriander seed extract in different level polarity of solvents. Maceration and extraction of coriander seeds was carried out using polar (ethanol), semipolar (ethyl acetate), and nonpolar (n-hexane) solvents. Phytochemical analysis, total flavonoid content, and total antioxidant capacity were performed on each extract. Statistical analysis was conducted using one-way ANOVA test. Phytochemical test showed that all extracts contained flavonoids, terpenoids and alkaloids. Glycosides are only found in ethyl acetate and hexane extracts. Ethanol extract had the highest flavonoid content compared to ethyl acetate extract and n-hexane extract. In addition, the highest total antioxidant capacity was found in the ethanol extract compared to the ethyl acetate extract and n-hexane extract, which was statistically significant. In conclusion, flavonoid content and total antioxidant capacity in Coriander seed extract is influenced by polarity of the solvent. Ethanol solvent for Coriander seed extract produce the highest flavonoid content and total antioxidant capacity.
Keywords: Coriander seed, flavonoid, total antioxidant capacity
