Light Exposure^s Effects on Inactive Frequency and Distance Moved of Zebrafish in Insomnia Model
Dheka Sapti Iskandar,Zamroni Afif, Husnul Khotimah, Irawan Satriotomo, Shahdevi Nandar Kurniawan, Annisatul Hakimah, Syafiatul Azizah, Nurvia Andriani, Kartika Agustina

Brawijaya University

Abstract

Insomnia as inability to maintain or elevate sleep quality at least three times a day, more than three days in a week, or more than three months. One of theories explaining insomnia causes focuses on a condition named hyperarousal, which is related to increasing mental, cognitive, and motor activities. This study is applied to insomnia model, that zebrafish larvae were exposed to a lamp with intensity of 200 lux. There were four phases of light exposure, are 12 hours of light, 12 hours of dark, 18 hours of light, and 6 hours of flash. The flash phase was divided into two, namely 2 minutes light (on) 2 minutes dark (off) and 4 minutes light 1 minute dark. The result is that the 24-hour treatment, both light and dark cycles, have a lower Inactive Frequency and a higher distance moved compared to the control group.

Keywords: Insomnia, Zebrafish, Inactive Frequency, Distance moved.

Topic: Biomedical Science